|
|
|
|
|
Back to List of Patient Handouts Print Friendly Version
Glucosamine Sulfate Glucosamine Sulfate is a superb product for its action in supporting healthy bone and connective tissue. Signs and Symptoms for Nutrient Applications- Osteoarthritis - Tissue and joint pain - Injury Clinical Applications/ResearchGlucosamine Sulfate Glucosamine sulfate (GS) is a fairly simple structure of glucose, an amine, and sulphur. GS provides the joints with the building blocks they need to repair damage to the cartilage. GS provides the raw material needed to manufacture glycosaminoglycans, a mucopolysaccharide found in cartilage. GS is found in high amounts in the joints, and a placebo-controlled, double-blind investigation reported that it affords some protection against destruction of the joints, such as in osteoarthritis (Drovanti, A. et al. Clin Ther. 1980; 3(4):260). Cartilage that was synthesized without GS contained few normal-sized chondroitin sulfate chains and only about half of the normal serine residues. Subsequent addition of GS resulted in a time-dependent recovery of sulfate incorporation after 2 hours, however the chondroitin sulfate chains were restored to normal size within 15 minutes. Glucosamine sulfate is, “required for optimal glycoconjugate synthesis” (Biochem J. 1991;273(Pt 2):283-8). Glucosamine sulfate is stabilized with one of two mineral salts: potassium chloride (KCl) or sodium chloride (NaCl). Both forms appear to be effective in stabilizing GS, but KCl is the preferred source since the Western diet is much higher in sodium and does not contain enough potassium. Dietary sources of glucosamine sulfate are not found in most diets, since GS is mainly derived from seashells. Suggested Dosage1500 mg daily (500 mg capsules (1 three times daily) or 750 mg capsules (one capsule twice daily)) Contraindications/ToxicologyAt the amount most frequently recommended in the literature (1500 mg per day), no toxicity has been reported. Disclaimer: The statements above have not been evaluated by the FDA. The nutritional suggestions and research provided are for informational purposes only and are not intended to diagnose, treat, cure or prevent disease and should not be used as a substitute for sound medical advice. Please see your health care professional in all matters pertaining to your physical health.
Copyright: Copyright
HealthQuest, Inc. All rights reserved. Information used with permission from the
HealthQuest Nutritional Database Version 4.0
|
 |
|
About Us
| Demo the Database |
Patient Handouts |
Links |
